Tolsama 15mg Tablet 4'S

Talk to your doctor before taking this medicine, if you: Are allergic to this medicine Suffer from kidney or liver disease Have an enlarged prostate Suffer from too high or too low blood sodium Have diabetes Have been told you have high levels of a chemical called uric acid in your blood

Always take this medicine exactly as your doctor has told you Swallow the tablet with a glass of water The morning dose is to be taken at least 30 minutes before the morning meal. The second daily dose can be taken with or without food If you take more TOLSAMA If you have taken more tablets than your prescribed dose, drink plenty of water and contact your doctor or your local hospital immediately If you forget to take TOLSAMA If you forget to take your medicine you should take the dose as soon as you remember on the same day If you do not take your tablets on one day, take your normal dose on the next day. Do not take a double dose to make up for forgotten individual doses If you stop taking TOLSAMA Do not stop taking TOLSAMA without your doctor advice

Like all medicines, this medicine can cause side effects, although not everybody gets them Difficult to urinate Swelling of the face, lips or tongue, itching, generalised rash or severe wheezing or breathlessness Worsening of liver problems

Tell your doctor if you are taking, have recently taken or might take any other medicines such as Ketoconazole, clarithromycin used to treat certain infections Digoxin a medicine for the treatment of irregular heart beat and heart failure Dabigatran medicine used to thin the blood Rosuvastatin or pitavastatin medicine used to lower blood cholesterol Methotrexate medicine used to treat cancer, arthritis Sulfasalazine medicine used to treat inflammatory bowel disease or rheumatoid arthritis Metformin medicine used for treatment of diabetes Phenytoin or carbamazepine medicine used for the treatment of epilepsy St.John’s wort herbal medicinal product for the relief of slightly low mood and mild anxiety Diuretics medicine used to increase your urine production Desmopressin medicine used to increase blood clotting factors or to control urine output or bedwetting

What is Autosomal dominant polycystic kidney disease” (ADPKD)? This disease causes growth of fluid-filled cysts in the kidneys which put pressure on surrounding tissues and reduce kidney function, possibly leading to kidney failure. TOLSAMA may cause your liver to not work properly. Therefore, please inform your doctor immediately if you have signs that could indicate potential liver problems such as: Nausea, vomiting, fever Tiredness Loss of appetite Pain in the abdomen Dark urine Jaundice (yellowing of skin or eyes) Itching of your skin Flu-like syndrome (joint and muscle pain with fever) During treatment with TOLSAMA, your doctor will arrange monthly blood tests to check for changes in your liver function