Duovir N Tablet 30'S

Talk to your doctor before taking this medicine, if you: Are hypersensitive (allergic) to lamivudine, zidovudine, nevirapine or any of the other ingredients of this medicine Have very low red blood cell count (severe anaemia) or very low white blood cell count (neutropenia) Have permanent liver disease or marked changes in liver function Are suffering from or have ever suffered from kidney disease Have Hepatitis B or C co-infection

Always take DUOVIR N exactly as your doctor or healthcare provider told you You should check with your doctor, health care provider if you are not sure The recommended dose of DUOVIR N in adults and children with a body weight of 25 kg or more is one tablet twice daily The tablet can be taken with or without food If you take more DUOVIR N If you have taken too many tablets contact your doctor, health care provider or the nearest hospital emergency department immediately If you forget to take DUOVIR N If you miss a dose and notice within 6 hours take the missed dose as soon as possible Take the next regular dose as scheduled If you notice later, then simply take your normal dose when the next one is due Do not take a double dose to make up for forgotten individual doses If you stop taking DUOVIR N You should not stop treatment unless your doctor or health care provider tells you to

Like all medicines, DUOVIR N can cause side effects, although not everybody gets them. Severe and life-threatening cutaneous reactions and serious hepatic injuries Osteonecrosis (death of bone tissue) Lactic acidosis Immune reactivation syndrome - signs and symptoms of inflammation from previous infections

Tell your doctor, if you are taking: Rifampicin (used to treat tuberculosis) Stavudine, emtricitabine, efavirenz, several protease inhibitors (e.g. tipranavir/rtv, atazanavir/rtv, fosamprenavir, indinavir) Ribavirin (antiviral agents) Ketoconazole, itraconazole (antifungals) Probenecid (uric acid lowering agent) Oral contraceptives the pill Fluconazole (antifungal medicine) Clarithromycin, rifabutin (antibiotics) Artemisinin’s, amodiaquine/artesunate, quinine, lumefantrine, halofantrine, atovaquone (antimalarials) Phenytoin, valproic acid (anticonvulsants) Warfarin (medicine for prophylaxis of blot clots) Doxorubicin (anti-cancer medicine) Herbal preparations containing St. John’s Wort

Storage Keep this medicine out of reach of children Do not use this medicine after the expiry date Store at room temperature (15-25°C)